Help us help you. By posting the year, make, model and engine near the beginning of your help request, followed by the symptoms (no start, high idle, misfire etc.) Along with any prevalent Diagnostic Trouble Codes, aka DTCs, other forum members will be able to help you get to a solution more quickly and easily!
Random misfire code p0300. This is the only code that is showing up. B1S1 is showing lean while B1S2 is reading rich. Both will respond to snap throttle. If I unplug ignition coil one at a time, there is a significant amount of RPM drop on cylinders 1,2, and 3. #4 there is no change in RPM. There is spark on #4 however and swapped coils, same thing. Fuel trims are normal.