Help us help you. By posting the year, make, model and engine near the beginning of your help request, followed by the symptoms (no start, high idle, misfire etc.) Along with any prevalent Diagnostic Trouble Codes, aka DTCs, other forum members will be able to help you get to a solution more quickly and easily!
What are the symptoms with your E350? I see some extreme fuel trims and a lazy looking B1S1 O2 sensor. If you could send that capture to me, I'd be happy to take a closer look.