2011 Buick Lacrosse cxs 3.6 V6, no start keeps popping #10 ecm fuse

2011 Buick Lacrosse cxs 140k+ miles, Wife parked car in driveway after going to store no codes or trouble before this. Later tried to start it and nothing no crank/no start engine light on dash flashing rapidly try hooking my basic scan tool and it says no communication. ecm relay clicking rapidly whenever I try and start it or open the doors trunk included. Found the ecm #10 fuse blown I replaced it,  it will crank but no start I have to hit the start/stop button to stop it from cranking then I check the fuse and it is blown battery was low the first time this happened I charged the battery still same problem and thought it was a bad battery I tried jumping it off with my other car still same problem can that battery be the whole problem even if I tried jumping it or something else...help!!!!!

Wanted to see if I had a reference voltage at throttle body unplugged it had 4.80v left it unplugged put a new #10 ECM fuse, cranked it actually started but was running very rough stopped it checked ECM fuse it was not blown this time plugged throttle body back in try starting it, it started but ran very very rough and died. Hooked up my scanner had codes P216D, P2155, PO223, PO122, PO700 for whatever reason it's communicating now but if I crank it now and if it starts runs very rough for a few seconds then dies out. Being that we had no problems or codes before this I thinking bad ECM but I don't know how to test this to be sure.
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These codes look like they were set because of the loss of power from the blown fuse and from having the throttle body unplugged.
Just to be clear, the car now starts and runs and the ecm fuse is not blowing any more?

If it does crank and if runs it's very rough missing a lot and dies but #10 fuse does not blow

It does crank and if it does runs it's very rough and usually dies out quickly after not blowing #10 fuse strangely stopped blowing only after I unplugged the throttle body to check voltage.

I checked to see if it had spark and it does but very little to no fuel pressure at Schrader valve on fuel rail any help out there please!!!